
Southeast Missouri Vacations
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Find the Best Southeast Missouri Vacation Packages
Southeast Missouri Hotel Deals

The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is ¥13,835 per night from May 11 to May 12
¥13,835
¥15,606 total
includes taxes & fees
May 11 - May 12
9.2/10 Wonderful! (234 reviews)
"Very clean hotel with bar , restaurant and a casino attached."
Reviewed on Apr 24, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is ¥14,222 per night from May 4 to May 5
¥14,222
¥16,044 total
includes taxes & fees
May 4 - May 5
9.4/10 Exceptional! (1,003 reviews)
"Great stay!!"
Reviewed on Apr 25, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is ¥8,275 per night from May 4 to May 5
¥8,275
¥9,421 total
includes taxes & fees
May 4 - May 5
8/10 Very Good! (925 reviews)
"Easy to find"
Reviewed on Apr 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Southeast Missouri
Southeast Missouri State University
4.5/5(76 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Alley Spring & Mill
4.5/5(4 reviews)
Learn about the local history of Eminence with a stop at Alley Spring & Mill. While you're in the area, stroll along the riverfront.
What to do in Southeast Missouri

History Tour of Pythian Castle in Springfield Missouri
¥1,837
per adult
80% of travellers recommend

Night Ghost Tour of Pythian Castle in Springfield Missouri
¥2,937
per adult
100% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.