Find hotels in Southeast Missouri, MO from ￥7,706

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Apr 10 - Apr 11
Tomorrow
Apr 11 - Apr 12
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Apr 11 - Apr 13
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Apr 18 - Apr 20

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Compare 561 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"We enjoyed our stay both times on our vacation to New Orleans."
The price is ￥15,188
￥17,133 total
includes taxes & fees
May 4 - May 5
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (529)
"Nice"
The price is ￥12,409
￥13,429 total
includes taxes & fees
Apr 13 - Apr 14
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (916)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is ￥13,791
￥15,557 total
includes taxes & fees
Apr 27 - Apr 28
Drury Inn & Suites Cape Girardeau
The Riverview
Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (222)
"Very nice place "
The price is ￥14,055
￥15,856 total
includes taxes & fees
Apr 23 - Apr 24
The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
"It was a great hotel and the staff were very helpful to us with our kids at breakfast time. The kids loved getting popcorn from the staff after a long day of driving."
The price is ￥13,933
￥15,717 total
includes taxes & fees
Apr 16 - Apr 17
Drury Plaza Hotel Cape Girardeau Conference Center
Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (700)
"It was clean and the beds were actually very comfortable. They never refilled the conditioner in the shower but that was the only complaint. "
The price is ￥16,211
￥18,288 total
includes taxes & fees
Apr 18 - Apr 19
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Clean hotel. Friendly staff"
The price is ￥12,477
￥14,345 total
includes taxes & fees
Apr 15 - Apr 16
Pear Tree Inn Sikeston
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Everything was amazing..The clerk was super nice, the room was neat and clean how i like..I would stay at this hotel wherever I need a quick get away to relax."
The price is ￥10,507
￥11,853 total
includes taxes & fees
Apr 16 - Apr 17
Pear Tree Inn Cape Girardeau West
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (97)
"Very clean and updated"
The price is ￥13,573
￥15,313 total
includes taxes & fees
May 4 - May 5
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (711)
"Very nice hotel. The rooms were beautiful and breakfast was delicious"
The price is ￥14,304
￥16,159 total
includes taxes & fees
May 5 - May 6
Fairfield Inn & Suites by Marriott Poplar Bluff
Holiday Inn Express & Suites Perryville by IHG
Exterior

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (454)
"Recently remodeled. Friendly staff. Clean. "
The price is ￥15,033
￥17,209 total
includes taxes & fees
Apr 27 - Apr 28
Holiday Inn Express & Suites Perryville by IHG
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Very accommodating and friendly staff! Helpful with stressful travelers😊 Great breakfast and evening kick back snacks and drinks!"
The price is ￥13,134
￥13,886 total
includes taxes & fees
Apr 16 - Apr 17
Drury Inn & Suites Jackson MO
Courtyard by Marriott Cape Girardeau Downtown
Lobby

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (408)
"Amazing "
The price is ￥18,433
￥20,887 total
includes taxes & fees
May 11 - May 12
Courtyard by Marriott Cape Girardeau Downtown
Tru By Hilton Cape Girardeau
Room

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (5)
"New hotel. very nice."
The price is ￥14,763
￥16,803 total
includes taxes & fees
May 4 - May 5
Tru By Hilton Cape Girardeau
Comfort Inn Festus - St Louis South
Lobby

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (797)
"Nice full breakfast. Bed was comfortable."
The price is ￥13,026
￥15,221 total
includes taxes & fees
Apr 27 - Apr 28
Comfort Inn Festus - St Louis South
Motel 6 Poplar Bluff, MO
Blackout drapes, free WiFi, bed sheets

Motel 6 Poplar Bluff, MO

2.0 star property
8.0 out of 10, Very Good, (1001)
"😌"
The price is ￥11,530
￥12,162 total
includes taxes & fees
Apr 13 - Apr 14
Motel 6 Poplar Bluff, MO
Drury Inn & Suites Hayti Caruthersville
Lobby

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Clean rooms"
The price is ￥15,761
￥17,963 total
includes taxes & fees
Apr 27 - Apr 28
Drury Inn & Suites Hayti Caruthersville
Baymont Inn and Suites by Wyndham Farmington, MO
Business center

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (908)
"The beds were a bit hard. The restaurant adjoining the property was closed. "
The price is ￥7,706
￥8,773 total
includes taxes & fees
Apr 27 - Apr 28
Baymont Inn and Suites by Wyndham Farmington, MO
Super 8 by Wyndham Perryville
Exterior

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (844)
"The staff was very friendly and the guy at the front desk was helpful with ever thing we asked about hotel was nice clean and quiet. Thus was my second time staying at this same hotel"
The price is ￥10,153
￥11,623 total
includes taxes & fees
May 4 - May 5
Super 8 by Wyndham Perryville
Hampton Inn Poplar Bluff
Terrace/patio

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (691)
"Nice place"
The price is ￥14,143
￥15,838 total
includes taxes & fees
Apr 27 - Apr 28
Hampton Inn Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Apr 18 - Apr 20

Image gallery for La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
9.0/10Wonderful (529 reviews)
15% off
Price is ￥13,976
per night
￥30,250 total
includes taxes & fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

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