Search Guest Houses in Upstate South Carolina

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Compare 9 Guest Houses in Upstate South Carolina with updated reviews, rates, and availability.

✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.

10.0 out of 10, Exceptional, (65)
"We came in town to visit our kid at Furman. We were close, comfortable, and able to walk to the shops and restaurants in Travelers Rest. Very happy with the property and location. "
✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.

Private Suite in Downtown Simpsonville

10.0 out of 10, Exceptional, (57)
"My husband and I stayed here for a long weekend to start discovering the Greenville area and had a great time. Great shops just a walk across the street. Immaculate place to stay. There’s a covered porch right outside the entrance with two patio rocker seats and great breezes. A short drive away from a number of other towns and attractions. "
Private Suite in Downtown Simpsonville

Peaceful Lakefront Getaway Close to Clemson

10.0 out of 10, Exceptional, (33)
"This was a perfect get away place for a weekend out of busy clemson traffic but close enough to easily get to the campus for the game. Surrounding lake was beautiful and the property had plenty of space and opportunity for some fun for our 16 year old son. House was comfortable for talking and spending time together and the game room is a great place to use for more active gatherings. Just what we needed. "
Peaceful Lakefront Getaway Close to Clemson

Poolside Mountain Views and Outdoor Living

10.0 out of 10, Exceptional, (28)
"Just what we needed. A quiet, private and safe place to lay our head. My kids and I had a lovely couple of days at this wonderful guest suite. The grounds are beautiful and clean. Amenities are accurate as listed. We appreciated the warm welcome and nice pets. Thank you!!"
Poolside Mountain Views and Outdoor Living

Light and airy contemporary guest house with private deck and parking.

10.0 out of 10, Exceptional, (31)
"We would absolutely stay here again. We had the pleasure of meeting Bob and Barbara and taking stroll with them through the woods. Their loft is charming, spacious and very welcoming. This exceeded our expectations. Thank you for a wonderful stay. "
Light and airy contemporary guest house with private deck and parking.

Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.

9.2 out of 10, Wonderful, (18)
"Cottage was comfy, spacious, appealing, clean and convenient. Issues with entering unit due to conflicts between property details at VRBO website and host’s direct instructions, and due to unclear instructions regarding digital door lock. Shower has issue with hot water discontinuing intermittently. Was not addressed. Finally, Roku streaming device was missing from TV, so we were without TV. Sent many messages to host explaining that Roku streaming stick was not attached to TV before host agreed...
Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.

Downtown Greenville Lux Carriage House—Walk to Main St, SR Trail, The Well Arena

10.0 out of 10, Exceptional, (16)
"The accommodations were superb..just as described in the listing! The location was within walking distance of downtown and all major attractions. The host couldn’t be more inviting and accommodating. You would not be disappointed."
Downtown Greenville Lux Carriage House—Walk to Main St, SR Trail, The Well Arena

Updated, Spacious 6br/4ba -Simpsonville

10.0 out of 10, Exceptional, (1)
"We were in town for a wedding and this was the perfect space for my grown children and myself. We had plenty of space. The unit was clean, quiet, and the owners were easy to communicate with. We would stay there again."
Updated, Spacious 6br/4ba -Simpsonville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Upstate South Carolina
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Upstate South Carolina

Mint House Greenville - Downtown

4.0 star property
9.4 out of 10, Exceptional, (655)
"Easy In / Easy. out. "
The price is ¥19,069
¥21,549 total
includes taxes & fees
May 26 - May 27
Mint House Greenville - Downtown

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is ¥12,798
¥19,552 total
includes taxes & fees
May 13 - May 14
Postcard Cabins Lake Hartwell

Wooded Cottage - 3 Mi to Clemson University

3.0 star property
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.