Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.
Members save 10% more on select hotels, cars, activities and vacation rentals. Sign up.
Enjoy maximum flexibility with penalty-free cancellation on most car rentals.
Find Popular Airports close to Upstate South Carolina
Find Other Car Classes in Upstate South Carolina
- Mini car rentals in Upstate South Carolina
- Economy car rentals in Upstate South Carolina
- Compact car rentals in Upstate South Carolina
- Midsize car rentals in Upstate South Carolina
- Standard car rentals in Upstate South Carolina
- Fullsize car rentals in Upstate South Carolina
- Premium car rentals in Upstate South Carolina
- Luxury car rentals in Upstate South Carolina
- Convertible car rentals in Upstate South Carolina
- Minivan car rentals in Upstate South Carolina
- Van car rentals in Upstate South Carolina
- SUV car rentals in Upstate South Carolina
- Pickup car rentals in Upstate South Carolina
Expedia's Latest Trends
Hotels
General
Visit Long IslandVisit Catalina IslandVisit Florida PanhandleVisit Aleutian IslandsVisit Upstate New YorkVisit Greenville - SpartanburgVisit White MountainsVisit Silicon ValleyVisit Whidbey IslandVisit Bay AreaVisit HamptonsVisit Cape CodVisit Glen Canyon National Recreation AreaVisit Cape May - Wildwood