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Find hotels in South Main, Houston from ￥9,229

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Discover 6,328 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (742)
"I was very pleasantly surprised with this hotel. It is extremely clean and mostly in good repair. The staff was very friendly and attentive. The beds were comfortable. The water was hot and the room was spacious. It was an easy walk to NRG Stadium, which was a highlight for us since we were there for a game. I would not hesitate to stay at this hotel again if I go back for another football game. "
The price is ￥15,473
￥18,104 total
includes taxes & fees
Jan 26 - Jan 27
Comfort Suites near Texas Medical Center - NRG Stadium
Wyndham Houston near NRG Park/Medical Center
View from property

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1007)
"Rooms were good, beds were comfy. Place is showing its age but is kept as nice as possible. Very convenient if you're attending NRG stadium. Would stay again for the beds, staff, and convenience."
The price is ￥17,152
￥20,068 total
includes taxes & fees
Jan 4 - Jan 5
Wyndham Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center, an IHG Hotel
Exterior

Candlewood Suites Houston Medical Center, an IHG Hotel

2.5 star property
7.6 out of 10, Good, (725)
"Probably will not stay there again. Other properties in the area are much better. Homeless camped out right in front of the building. "
The price is ￥10,071
￥11,783 total
includes taxes & fees
Jan 15 - Jan 16
Candlewood Suites Houston Medical Center, an IHG Hotel
Wingate Houston near NRG Park/Medical Center
Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.8 out of 10, (796)
"Perfect hotel to stadium was the best feature for us will definitely come back. "
The price is ￥14,005
￥16,385 total
includes taxes & fees
Jan 4 - Jan 5
Wingate Houston near NRG Park/Medical Center
Tx Home Group - Medical Center
Shared kitchen

Tx Home Group - Medical Center

3.0 star property
6.8 out of 10, (3)
"If you dont want to stay in a apartment with a stranger, then this is NOT for you. The person i shared this apartment with was cool overall but almost burnt down the plcae 3x, the sharable portable fan stayed in her room, not considerable for others who may need to use washer and dryer and dishes to cook in, and played her music very loudly! When i booked this room i saw nothing saying "sharable" or else i would have used my $590 somewhere else but once paid it was non-refundable. Be aware...
The price is ￥13,650
￥28,589 total
includes taxes & fees
Jan 5 - Jan 6
Tx Home Group - Medical Center
Quality Inn & Suites NRG Park - Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1002)
"It was cool for 1 night they do charge 100 for deposit fee when you get there plus your stay"
The price is ￥9,229
￥10,798 total
includes taxes & fees
Feb 1 - Feb 2
Quality Inn & Suites NRG Park - Medical Center
La Quinta Inn & Suites by Wyndham Deer Park
Exterior

La Quinta Inn & Suites by Wyndham Deer Park

2.5 star property
8.6 out of 10, Excellent, (358)
"Ok. Will return."
The price is ￥13,242
￥15,492 total
includes taxes & fees
Jan 4 - Jan 5
La Quinta Inn & Suites by Wyndham Deer Park
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillowtop beds, desk, iron/ironing board, free WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (871)
"Love that it is a gated property."
The price is ￥10,710
￥12,316 total
includes taxes & fees
Jan 26 - Jan 27
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Sonesta Simply Suites Houston – NASA Clear Lake
Fridge, microwave, stovetop, dishwasher

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very Good, (806)
"Nice hotel just there is no space to unload luggage from car to trolley."
The price is ￥9,284
￥10,862 total
includes taxes & fees
Jan 14 - Jan 15
Sonesta Simply Suites Houston – NASA Clear Lake
SureStay Hotel by Best Western Deer Park
In-room safe, individually furnished, desk, laptop workspace

SureStay Hotel by Best Western Deer Park

2.5 star property
8.4 out of 10, Very Good, (196)
" The room was nice as they gave me a first floor room per my request. Also. I was scheduled to come on a Thursday night for a Friday morning meeting. However, got word that my meeting was postponed to Monday at the last minute. I missed the deadline for cancellation/changes. So called to ask them to move reservation to Sunday night. They were kind to allow me to do this. "
The price is ￥9,914
￥11,601 total
includes taxes & fees
Jan 4 - Jan 5
SureStay Hotel by Best Western Deer Park
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Suite, 2 Queen Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free cribs/infant beds

La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA

2.5 star property
7.8 out of 10, Good, (1004)
"Great "
The price is ￥10,860
￥12,705 total
includes taxes & fees
Jan 26 - Jan 27
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Best Western Webster Hotel, Nasa
Seasonal outdoor pool, pool umbrellas, sun loungers

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1000)
"Best Western is a very nice and reasonable price place to stay."
The price is ￥10,463
￥12,243 total
includes taxes & fees
Jan 14 - Jan 15
Best Western Webster Hotel, Nasa
La Quinta Inn & Suites by Wyndham Houston Channelview
Exterior

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.6 out of 10, Excellent, (662)
"The only con was that breakfast ends at 9am on the weekends which is early for us since we were on vacation and trying to sleep in. I’ve been to other properties and it typically ends at 10 am. Overall the hotel was great. If I return to Houston I will definitely stay here!"
The price is ￥11,511
￥13,469 total
includes taxes & fees
Jan 26 - Jan 27
La Quinta Inn & Suites by Wyndham Houston Channelview
Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel
Exterior

Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel

2.5 star property
8.4 out of 10, Very Good, (340)
"Everything was nice neat and clean. Staff was very friendly and helpful."
The price is ￥12,746
￥14,913 total
includes taxes & fees
Jan 5 - Jan 6
Holiday Inn Express & Suites Houston East - Beltway 8, an IHG Hotel
La Quinta Inn & Suites by Wyndham Pasadena
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, iron/ironing board

La Quinta Inn & Suites by Wyndham Pasadena

2.5 star property
7.8 out of 10, Good, (655)
"Property is going through major renovations. The first room we were assigned was very rough. The beds were flat with rust in the bathroom. I asked the front desk clerk and she was over the top amazing. She personally took me to another room to inspect. "
The price is ￥12,038
￥14,084 total
includes taxes & fees
Jan 27 - Jan 28
La Quinta Inn & Suites by Wyndham Pasadena
Palace Inn Blue Houston East Beltway 8
Reception

Palace Inn Blue Houston East Beltway 8

2.5 star property
9.0 out of 10, Wonderful, (232)
"Very good"
The price is ￥10,256
￥11,795 total
includes taxes & fees
Jan 21 - Jan 22
Palace Inn Blue Houston East Beltway 8
La Quinta Inn & Suites by Wyndham Pasadena North
Lobby

La Quinta Inn & Suites by Wyndham Pasadena North

2.5 star property
8.0 out of 10, Very Good, (518)
"Front desk was friendly and helpful late check-in due to bad weather. The place is okay needs improvement the place smelled smokey and musty..Beware they charge 100 cash for incidental..I had no cash so waive for me...My negative was they hand you instructions on how yo use the shower..I thought it was a bit overprice for that Hotel..They serve breakfast and yes night shift prepares the food with a smokers cough..Better that most in the surroundings area.."
The price is ￥12,524
￥14,653 total
includes taxes & fees
Feb 2 - Feb 3
La Quinta Inn & Suites by Wyndham Pasadena North
Bluestar Inn
Individually furnished, desk, iron/ironing board, free WiFi

Bluestar Inn

2.5 star property
8.8 out of 10, Excellent, (189)
"Nice"
The price is ￥11,487
￥13,440 total
includes taxes & fees
Jan 5 - Jan 6
Bluestar Inn
Best Western Plus Heritage Inn
Reception

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very Good, (573)
"Overall experience was excellent!!"
The price is ￥12,321
￥14,417 total
includes taxes & fees
Jan 5 - Jan 6
Best Western Plus Heritage Inn
Woodspring Suites South Houston Hobby
Suite, 1 King Bed, Non Smoking | Individually furnished, desk, laptop workspace, bed sheets

Woodspring Suites South Houston Hobby

2.5 star property
7.8 out of 10, Good, (117)
"Awesome place!!!"
The price is ￥9,284
￥10,862 total
includes taxes & fees
Jan 4 - Jan 5
Woodspring Suites South Houston Hobby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 66 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.