Photo by Hazem Abdul

Find hotels in South Main, Houston from ¥11,519

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Discover 6,115 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Club Quarters Hotel Downtown, Houston
4.0 star property
8.2 out of 10, Very Good, (3066)
"it was great"
The price is ¥15,117
¥17,687 total
includes taxes & fees
Dec 5 - Dec 6
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.0 out of 10, Very Good, (1522)
"All staff is very welcoming! "
The price is ¥17,584
¥20,718 total
includes taxes & fees
Dec 4 - Dec 5
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
4.0 star property
8.4 out of 10, Very Good, (1070)
"The staff was amazing and very accommodating!"
The price is ¥19,338
¥22,625 total
includes taxes & fees
Nov 26 - Nov 27
The Whitehall Houston
Blossom Hotel Houston
4.0 star property
9.2 out of 10, Wonderful, (2812)
"Food at the blossom restaurant was delicious, however I was served bacon and Ham on my sandwich after letting them know I was allergic, I brought it up to the attention of the manager Tamika and she was awesome, she made it right and made sure I was satisfied and assured me they would look into the communication breakdown "
The price is ¥18,365
¥21,488 total
includes taxes & fees
Nov 25 - Nov 26
Blossom Hotel Houston
Holiday Inn Houston Downtown, an IHG Hotel
3.0 star property
8.6 out of 10, Excellent, (1000)
"Awesome hotel staff and wonderful downtown shuttle service."
The price is ¥11,519
¥16,150 total
includes taxes & fees
Nov 28 - Nov 29
Holiday Inn Houston Downtown, an IHG Hotel
Marriott Marquis Houston
4.0 star property
8.8 out of 10, Excellent, (1013)
"More time for the price, it's worth it. I like everything except the little time they give you to spend in the hotel."
The price is ¥35,498
¥46,774 total
includes taxes & fees
Nov 27 - Nov 28
Marriott Marquis Houston
Hilton Americas-Houston
4.0 star property
9.2 out of 10, Wonderful, (1120)
"This hotel is absolutely awesome, staff is great. Location is good and has all the amenities that makes for a great stay. "
The price is ¥23,168
¥27,461 total
includes taxes & fees
Nov 26 - Nov 27
Hilton Americas-Houston
Hyatt Regency Houston Downtown
4.0 star property
9.2 out of 10, Wonderful, (1008)
"This property was amazing!!!! Everything was 10-15 minutes walking distance. The staff were super friendly! Justina and Doris were amazing CSRs. Definitely recommend this hotel. "
The price is ¥25,734
¥31,045 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Regency Houston Downtown
Hyatt Place Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (1423)
"good for the price"
The price is ¥17,701
¥21,100 total
includes taxes & fees
Nov 22 - Nov 23
Hyatt Place Houston Downtown
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.4 out of 10, Very Good, (906)
"Beautiful, modern hotel!"
The price is ¥24,462
¥32,655 total
includes taxes & fees
Nov 24 - Nov 25
C. Baldwin, Curio Collection by Hilton
Rusk House Serviced Apartments
4.5 star property
9.2 out of 10, Wonderful, (76)
"Very friendly reception team on arrival and the apartment itself is a great size, very comfortable with useful amenities. There’s a tram stop just around the corner to the block taking you to the museum district easily and there are a number of food options locally. Recommended."
The price is ¥21,318
¥24,942 total
includes taxes & fees
Nov 17 - Nov 18
Rusk House Serviced Apartments
Le Meridien Houston Downtown
4.0 star property
8.6 out of 10, Excellent, (859)
"Stayed2 nights, great location, rooftop bar great "
The price is ¥24,241
¥28,362 total
includes taxes & fees
Nov 17 - Nov 18
Le Meridien Houston Downtown
Hyatt Place Houston Medical Center
3.0 star property
9.0 out of 10, Wonderful, (1124)
"Staff was courteous and kind! Many wonderful amenities!"
The price is ¥16,696
¥19,635 total
includes taxes & fees
Dec 1 - Dec 2
Hyatt Place Houston Medical Center
Cambria Hotel Houston Downtown Convention Center
3.0 star property
8.8 out of 10, Excellent, (1443)
"We had a very quiet room. The beds are very comfy! "
The price is ¥17,474
¥20,444 total
includes taxes & fees
Dec 1 - Dec 2
Cambria Hotel Houston Downtown Convention Center
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
3.5 star property
7.4 out of 10, Good, (1001)
"Desk service at check in was pretty average. Not overly friendly by any means. Room was ok. TV is small. Bathtub drain wasn't functioning properly. Hotel bar/restaurant was ok. Food was decent. Bar tender was nice."
The price is ¥13,552
¥15,856 total
includes taxes & fees
Nov 10 - Nov 11
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
Moxy Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (251)
"I like that there's a butch of bar and clubs in walking distance"
The price is ¥15,075
¥17,942 total
includes taxes & fees
Nov 24 - Nov 25
Moxy Houston Downtown
Thompson Houston, by Hyatt
4.0 star property
9.2 out of 10, Wonderful, (88)
"wonderul property and beautiful "
The price is ¥42,346
¥56,047 total
includes taxes & fees
Nov 25 - Nov 26
Thompson Houston, by Hyatt
The Royal Sonesta Houston Galleria
4.0 star property
8.2 out of 10, Very Good, (1002)
"They put us on the third floor overlooking generator units. Disgusting view. Rooms are due to be refreshed."
The price is ¥20,788
¥28,259 total
includes taxes & fees
Dec 1 - Dec 2
The Royal Sonesta Houston Galleria
InterContinental Houston, an IHG Hotel
4.0 star property
9.2 out of 10, Wonderful, (1015)
"The stay was perfect from start to finish. Check in was a breeze, and the room was decked with luxurious amenities from the Byredo bathroom products to the softest terry cloth robe with matching slippers. I ordered room service and the meal delivery was prompt and seamless. I thought the food and coffee from the adjacent restaurant were a bit pricey but was totally worth it for the convenience. The hotel’s proximity to the Museum District and the cool, hipster shopping and restaurants in...
The price is ¥19,338
¥24,910 total
includes taxes & fees
Nov 28 - Nov 29
InterContinental Houston, an IHG Hotel
The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
8.8 out of 10, Excellent, (1008)
"Staff is always accommodating. "
The price is ¥22,650
¥26,500 total
includes taxes & fees
Nov 17 - Nov 18
The Chifley Houston, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 68 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.