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Compare 61 Vacation Homes in Santee with updated reviews, rates, and availability.

Lake Marion Lakehouse with 180° lake view
10.0 out of 10, Exceptional, (44)
"The key Code did not work to begin with but we figured it out after talking with the owner.. The sliding door in the bedroom will not open, even after removing the bar in the door. Maybe the track needs vaccuming out.?? No clue. Place is BEATIFUL!!!! Very Quite and peaceful!!! The floors could have used a bit of sweeping but wasnt a big deal. We swept them and again before we left also."
Lake Marion Lakehouse with 180° lake view
Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
10.0 out of 10, Exceptional, (129)
"House was very clean and comfortable. Large well furnished kitchen. Really enjoyed the large relaxing sunroom that gave a great view of the lake. Nice Dock on deep water. "
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
9.8 out of 10, Exceptional, (220)
"There was 14 of us total. There was plenty of room for everyone comfortably. The yard was beautiful. The enclosed back patio was used quite a bit. We definitely enjoyed our stay at the property. "
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
9.8 out of 10, Exceptional, (71)
"This property did not disappoint. We had a wonderful time. It is as described. Loved the location on the water. "
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, (25)
"Property is in excellent condition. Comunication with owner was great . And the location near the lake is beautiful. Defenlly recommend. And will look for this property first when im in The area again"
The price is ¥17,511
¥50,971 total
includes taxes & fees
Oct 6 - Oct 7
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
2.0 star property
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
The Bunkhouse at St Julien - Vintage Waterfront Lake House
9.8 out of 10, Exceptional, (13)
"The property was more impressive in person. The inside and outside areas were more than comfortable and accommodating. The outside TV was nice to enjoy the football game and the weather, the comfortable breezes while having views of the water. Kitchen was spacious enough for multiple people to be able to prep and cook meals. Outside grills were great. Very dog friendly. I could type for a while describing all the positives about this property. A weekend is not a long enough time to enjoy all...
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Taw Caw Creek Rental - perfect for fishermen - NO PETS
10.0 out of 10, Exceptional, (11)
"First I would like to say this is the cleanest place I been in. Very peaceful and perfect place to relax after a day on the lake. Thanks will be back for sure. "
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Relax by Lake Marion - A lake home with you in mind.
9.4 out of 10, Exceptional, (63)
"Even though tropical storm sat on us for 4 days we (my wife and 2 daughters, 20 and 22) had a great. The house had more than enough room for us and plenty of games and puzzles. We were able to get the kayaks in the water at least 2 days. Nice place and had a good time."
Relax by Lake Marion - A lake home with you in mind.
Cozy & Peaceful 3 bed 2 bath On the Water
10.0 out of 10, Exceptional, (26)
"Had a wonderful long weekend getaway. Great accommodations and location. Kathy even ordered us perfect weather😊. Communication was easy and prompt. Thanks again for sharing your home!"
Cozy & Peaceful 3 bed 2 bath On the Water
Beautiful Cottage between Lake Moultrie and Lake Marion
9.8 out of 10, Exceptional, (125)
"Everything my wife and I needed for a nice fishing trip. Great location. Host answered swiftly when we had a question. Cant wait to go back. This was our second time renting the A frame house. Neighbors were quiet and nice to talk with, great time."
Beautiful Cottage between Lake Moultrie and Lake Marion
Archie's Lake Daze Cottage
10.0 out of 10, Exceptional, (61)
"A great place to relax."
Archie's Lake Daze Cottage
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
9.0 out of 10, Wonderful, (19)
"Was very enjoyable and peaceful.."
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Tom Charles Goat Island Fishing Retreat
9.8 out of 10, Exceptional, (43)
"Great place to stay for families. Fishing tournaments guys this is all you need, close to ramp amd restaurant. Not far from town."
Tom Charles Goat Island Fishing Retreat
Lakefront Stay on Santee
9.8 out of 10, Exceptional, (6)
"We left a review in the book at the house. The beds were not the sizes described on website, There was dust, cobwebs and mold all throughout the house. There were also not enough Kitchen essentials for us to cook. "
Lakefront Stay on Santee
Jewel on the Lake - Relaxing Lakefront Home
9.6 out of 10, Exceptional, (15)
"Cottage was updated, clean and well maintained. Owner was very responsive and great to deal with. Highly recommended."
Jewel on the Lake - Relaxing Lakefront Home
Golf and Lake fun on Santee! Bring your boat or golf clubs!
9.4 out of 10, Exceptional, (23)
"We enjoyed the house... The house has beautiful wood floors......The photos on the VRBO of the lake were misleading that the property was on the LAKE!!! ..."
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Fabulous Location on southern shores of Lake Marion
9.4 out of 10, Exceptional, (10)
"This property was over the top and way above my expectations. Highly recommend."
Fabulous Location on southern shores of Lake Marion
Dukes Street Retreat 5min from I-95!
8.0 out of 10, Very Good, (10)
"We felt so special staying in such a beautiful home! It was well stocked and laid out perfectly for a wonderful family time. Nice neighborhood. We felt perfectly safe."
Dukes Street Retreat 5min from I-95!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Santee

Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Executive 2 BR/2 BA Lakefront Corner Suite Condo
9.0 out of 10, Wonderful, (28)
"We came for the weekend my Hubbys birthday! My parents and sister and hubby visited for a few hours to celebrate. Very spacious, neat clean - very homey, but on the lake. Kitchen very stocked with pans dishes even a crock pot! Can’t wait to visit again! Hopefully weather will cooperate next time."
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, (25)
"Property is in excellent condition. Comunication with owner was great . And the location near the lake is beautiful. Defenlly recommend. And will look for this property first when im in The area again"
The price is ¥17,511
¥50,971 total
includes taxes & fees
Oct 6 - Oct 7
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.