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Feb 23 - Feb 24
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Feb 24 - Feb 25
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Feb 28 - Mar 2
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Mar 7 - Mar 9

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Compare 37 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

To Spiti tis Sofias
Interior

To Spiti tis Sofias

The price is ￥7,794
￥8,929 total
includes taxes & fees
Mar 11 - Mar 12
To Spiti tis Sofias
Guest House Ilektra
Hiking

Guest House Ilektra

9.6 out of 10, Exceptional, (5)
"We were doing a project in nearby Pentalofos so we had long work days. The area is quiet and it's a wonderful departure from the business of the city. The rooms were quite comfortable and my room had everything I needed. I had a small fridge and a stove to cook up anything if I wanted. Part way through my trip I was able to coordinate laundry services. My room had a wonderful view of the sunrise, which was a great sight to wake up to. The rooms are always clean and warm, it felt like a home...
The price is ￥6,873
￥7,883 total
includes taxes & fees
Feb 23 - Feb 24
Guest House Ilektra
Limneon Resort & Spa
Turkish bath, body treatments, hot stone massages

Limneon Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (173)
"We loved everything about the hotel. It was truly a 5 star, luxury hotel. We booked a Seaview room - the room and bathroom were modern and luxurious with a rain shower , bathrobes, fluffy towels and everything you would expect. When we walked in, the lobby was grand, check-in was a breeze, and service was excellent. There is even a hair salon and separately a spa which was wonderful. Breakfast was plentiful and the pool was nice with cabanas and lounge chairs. It’s on the seaside and an...
The price is ￥14,000
￥16,367 total
includes taxes & fees
Feb 23 - Feb 24
Limneon Resort & Spa
Hotel Anastassiou
Front of property - evening/night

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very Good, (60)
"Nice hotel. Nice room. Nice people!! Not walkable to town but a very short drive! And a very lovable property pup!! Thank you for your hospitality!! "
The price is ￥5,980
￥6,868 total
includes taxes & fees
Mar 17 - Mar 18
Hotel Anastassiou
Orologopoulos Mansion
Deluxe Double or Twin Room | Minibar, in-room safe, soundproofing, iron/ironing board

Orologopoulos Mansion

5.0 star property
9.6 out of 10, Exceptional, (33)
"This was a wonderful stay in a wonderful hotel and surrounds, the type of village you envision in a small greek community. The hotel had tradtional atmosphere, an beautiful porch area and was just off the square. My only grievance was how uncomfortable the mattresses were. I had a hard time getting comfortable and woke up sore from how hard the bed was."
The price is ￥13,265
￥15,689 total
includes taxes & fees
Feb 23 - Feb 24
Orologopoulos Mansion
Andromeda Boutique hotel
Exterior

Andromeda Boutique hotel

4.0 star property
8.8 out of 10, Excellent, (3)
The price is ￥11,272
￥14,830 total
includes taxes & fees
Mar 5 - Mar 6
Andromeda Boutique hotel
Anesis Hotel
Pool

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
"It suited my purpose. Nothing fancy, but adequate. Only disappointed that when I arrived early all the way from America, they didn't allow me to check in for several hours when the place was empty, and they didn't offer to let me leave my heavy backpack with them while I waited. I had to walk around with it for a long time. Also, it was a hot day, and when I asked how to use the air conditioner in the room, rather then just pleasantly give me the remote for it, I had to hear a comment about it...
The price is ￥6,873
￥7,883 total
includes taxes & fees
Feb 24 - Feb 25
Anesis Hotel
Kyknos De Luxe Hotel
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Kyknos De Luxe Hotel

10.0 out of 10, Exceptional, (42)
"Very nice clean, very polite staff and great breakfast!"
The price is ￥11,600
￥13,407 total
includes taxes & fees
Mar 17 - Mar 18
Kyknos De Luxe Hotel
Esperos Palace Luxury & Spa Hotel
Lobby sitting area

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
"very good hotel, very large room, lake view, modern design, nice and tasty breakfast, quiet surrounding, "
The price is ￥17,891
￥20,786 total
includes taxes & fees
Feb 23 - Feb 24
Esperos Palace Luxury & Spa Hotel
Chloe Hotel
Luxury Suite, Lake View | Living area | LED TV

Chloe Hotel

3.0 star property
10.0 out of 10, Exceptional, (79)
"Safe , quiet ,convenient and easy parking. Very accommodating Staff and delicious breakfast "
The price is ￥12,371
￥14,284 total
includes taxes & fees
Mar 8 - Mar 9
Chloe Hotel
Guesthouse Vissinokipos
Garden

Guesthouse Vissinokipos

9.4 out of 10, Exceptional, (10)
"Lovely view."
The price is ￥10,887
￥12,442 total
includes taxes & fees
Mar 4 - Mar 5
Guesthouse Vissinokipos
Calma Hotel & Spa
Property grounds

Calma Hotel & Spa

4.0 star property
9.6 out of 10, Exceptional, (31)
"Great place to relax. Very kind staff all over. Nice breakfast buffet."
The price is ￥12,268
￥14,401 total
includes taxes & fees
Mar 5 - Mar 6
Calma Hotel & Spa
Guesthouse Monopati
Basic Double Room | Free WiFi

Guesthouse Monopati

10.0 out of 10, Exceptional, (2)
The price is ￥10,007
￥11,442 total
includes taxes & fees
Feb 23 - Feb 24
Guesthouse Monopati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesopotamia

Head to Kastoria Aquarium and Kastoria Lake—just two of the sights around Mesopotamia.

See all hotels in Mesopotamia

Frequently asked questions

Where is the best place for a stay in Mesopotamia?

To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Chloe Hotel. See all available top hotels, or vacation rentals in Mesopotamia.

What are some of the best vacation home rentals that Mesopotamia has to offer?

The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη: This vacation home rental outside of Mesopotamia is located on a lake and has a fireplace, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, an oven, and a microwave. See all vacation rentals in Mesopotamia.

If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?

Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.

Where can I learn more about changing or cancelling my trip to Mesopotamia?

For more details about picking new dates or cancelling your trip to Mesopotamia, click here.

What are some hotels with pools in Mesopotamia?

Limneon Resort & Spa: Features an indoor pool, an outdoor pool, and a sauna. Calma Hotel & Spa and Loggas Hotel are a couple of other choices with an onsite pool.

What is the best accommodation for staying close to Macedonia Airport (SKG)?

Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.

What is staying in Mesopotamia like?

Travelers to Mesopotamia will find plenty to explore and enjoy. There are 37 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.

What are the top places to visit in Mesopotamia?

Places to visit in the wider area include Kastoria Aquarium, Kastoria Lake, and Neolithic Lakeside Settlement. You'll also find Byzantine Museum of Kastoria and Dragon's Lair in the area. Check out what more to see and do in Expedia's Mesopotamia guide.

What's the seasonal weather like in Mesopotamia?

The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.