Uptown - Upper Duval, FL

Key West

Key West Butterfly and Nature Conservatory featuring zoo animals, animals and flowers
Key West Butterfly and Nature Conservatory showing zoo animals, animals and flowers
South Beach which includes a beach and a coastal town as well as a large group of people
South Beach showing a beach, swimming and a luxury hotel or resort
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point featuring signage as well as a large group of people

Southernmost Point

4.5/5(3,182 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach featuring a sandy beach and general coastal views as well as a small group of people

South Beach

4/5(980 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing animals, zoo animals and food

Key West Butterfly and Nature Conservatory

4.5/5(760 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

￥2,329
per traveler
76% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

￥2,283
per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Bahama Village Walking Tour

Bahama Village Walking Tour

￥4,569
per adult
Bahama Village Walking Tour
Key West History And Culture Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

￥6,091
per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour Via App

￥1,369
per traveler
Florida Key West Self-Guided Walking Audio Tour Via App
Climb the 88 stairs to the top of the Key West Lighthouse.

Maritime Village to Micro State: A Self Guided Tour of Key West

￥1,826
per adult
Maritime Village to Micro State: A Self Guided Tour of Key West
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is ￥64,820 per night from Feb 25 to Feb 26
￥64,820
￥82,998 total
includes taxes & fees
Feb 25 - Feb 26
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,283 reviews)
"Great location. Walk to lots of sites and dining options. Loved the tranquility pool."

Reviewed on Feb 22, 2025

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is ￥62,574 per night from Mar 3 to Mar 4
￥62,574
￥79,799 total
includes taxes & fees
Mar 3 - Mar 4
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (856 reviews)
"Great beach and staff. Beautiful property. Highly recommend!"

Reviewed on Feb 20, 2025

The Reach Key West, Curio Collection by Hilton
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is ￥37,501 per night from Feb 23 to Feb 24
￥37,501
￥46,388 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,064 reviews)
"Great property"

Reviewed on Feb 19, 2025

Southwinds Motel
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is ￥43,139 per night from Feb 23 to Feb 24
￥43,139
￥55,248 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,020 reviews)
"Perfect! The property was clean, quiet, and absolutely gorgeous. The staff was friendly and helpful. Even the other guests were engaging and friendly. We will stay here again!!!"

Reviewed on Feb 21, 2025

The Southernmost Inn - Adults Only
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is ￥50,924 per night from Feb 23 to Feb 24
￥50,924
￥59,295 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Southernmost Point and Duval Street are ...
9.4/10 Exceptional! (32 reviews)
Key West vacation
"Super amazing place to stay! Walked everywhere and never had to take our car out of its spot. Will definitely come back!"

Reviewed on Feb 20, 2025

Douglas House
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is ￥81,949 per night from Feb 23 to Feb 24
￥81,949
￥96,788 total
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3-star beach hotel in Key West. Enjoy free breakfast, room service, and parking (surcharge). Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,002 reviews)
"The staff was very friendly and helpful. The room was delightful and very clean. Breakfast was very good. We loved spending time on the balcony and at the heated pool. We loved having the resort feel with no crowd."

Reviewed on Feb 22, 2025

The Mansion on the Sea - Southernmost House in the USA
See all 2,950 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

4.5/5(226 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(38 area reviews)

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(4,033 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval, FL