Find hotels in Isla Santa María from ¥7,523

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Isla Santa María hotel prices

Tomorrow night
This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 200 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Floreana Island

2.0 star property
Floreana Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Isla Santa María
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

Where is the best place for a stay in Isla Santa María?

Located 39 mi (62.7 km) from the heart of Isla Santa María, Hotel el descanso del Guia is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Blu Galapagos Sustainable Waterfront Lodge and Hotel Fiesta. See all available top hotels, or vacation rentals in Isla Santa María.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.

If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.

Where can I learn more about changing or cancelling my trip to Isla Santa María?

For more details about updating your trip to Isla Santa María or cancelling it, click here.

What is staying in Isla Santa María like?

Travelers to Isla Santa María will find plenty to explore and enjoy. There are 200 hotels and other accommodations in larger region. Find out more about Isla Santa María.

What should I see while I'm in Isla Santa María?

Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.

What's the weather like in Isla Santa María?

The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.