Find Business Hotels in Downtown San Diego, CA

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Check availability on Downtown San Diego Business Hotels

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Compare Downtown San Diego Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel

3.5 star property
8.2 out of 10, Very Good, (1431)
"The Sophia was a great place to stay. Conveniently located within walking distance to many restaurants and the pier. Room was clean and comfortable. The filtered water stations to refill my water bottle was super convenient and tasted great. "
The price is ¥22,883
¥29,139 total
includes taxes & fees
Mar 4 - Mar 5
The Sofia Hotel

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (5617)
"Only downside for me was cost to park a car ($50/day)"
The price is ¥24,022
¥27,072 total
includes taxes & fees
Mar 16 - Mar 17
Wyndham San Diego Bayside

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2217)
"I travel a lot to San Diego and I stay at The Horton Grand every time. My favorite Hotel and bar. Excellent whisky selection."
The price is ¥21,550
¥28,324 total
includes taxes & fees
Mar 18 - Mar 19
The Horton Grand, Downtown/Gaslamp Quarter

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2809)
"Nice location and hotel!"
The price is ¥28,212
¥38,888 total
includes taxes & fees
Mar 6 - Mar 7
Manchester Grand Hyatt San Diego

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1157)
"The room was very clean and functional, if not large. I was disappointed to be on the ground floor so it was very dark and maintenance staff was working outside the window, but the location is fantastic. A great farmer’s market on Saturday mornings is just around the corner, totally worth a stroll, and the trolley is also close."
The price is ¥20,181
¥22,301 total
includes taxes & fees
Mar 16 - Mar 17
Urban Boutique Hotel

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very Good, (1524)
"Great location. Under staffed "
The price is ¥27,084
¥37,613 total
includes taxes & fees
Mar 14 - Mar 15
Hilton San Diego Bayfront

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2577)
"It was a great stay staff super professional "
The price is ¥23,764
¥33,510 total
includes taxes & fees
Feb 23 - Feb 24
Hard Rock Hotel San Diego

Comfort Inn Gaslamp Convention Center

2.5 star property
7.8 out of 10, Good, (1004)
"Clean and reasonable rates"
The price is ¥15,282
¥17,221 total
includes taxes & fees
Mar 6 - Mar 7
Comfort Inn Gaslamp Convention Center

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
8.8 out of 10, Excellent, (1141)
"Property was very nice. The food for breakfast needs a little help. The happy hour was ok. Other than that amazing stay."
The price is ¥32,862
¥41,241 total
includes taxes & fees
Mar 14 - Mar 15
Embassy Suites by Hilton San Diego Bay Downtown

Sheraton San Diego Resort

4.0 star property
8.0 out of 10, Very Good, (2564)
"Love the hotel and the views are spectacular"
The price is ¥25,227
¥34,486 total
includes taxes & fees
Mar 7 - Mar 8
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.