Find Business Hotels in Downtown San Diego, CA

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Compare Downtown San Diego Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel

3.5 star property
8.2 out of 10, Very Good, (1394)
"Small rooms, convenient location. No restaurant."
The price is ¥17,397
¥23,115 total
includes taxes & fees
Dec 24 - Dec 25
The Sofia Hotel

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (5544)
"The Bayview is nine and it is close to the city center."
The price is ¥23,783
¥26,803 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Wyndham San Diego Bayside

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
8.8 out of 10, Excellent, (2154)
"The property was well maintained. Our room was clean, and the staff came every day to fix the room and remove trash. The one thing I disliked about the hotel was that we had an issue with the light at the room's entryway. The maintenance guy just knocked and immediately opened the door without waiting to be let in, which I found to be very unprofessional."
The price is ¥20,838
¥27,712 total
includes taxes & fees
Dec 23 - Dec 24
The Horton Grand, Downtown/Gaslamp Quarter

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2839)
" Good in general"
The price is ¥26,416
¥37,206 total
includes taxes & fees
Dec 23 - Dec 24
Manchester Grand Hyatt San Diego

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1179)
"Great place in the heart of little Italy. Excellent service. Definitely recommend."
The price is ¥17,139
¥18,938 total
includes taxes & fees
Dec 23 - Dec 24
Urban Boutique Hotel

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very Good, (1507)
"Great hotel"
The price is ¥17,468
¥27,131 total
includes taxes & fees
Jan 5 - Jan 6, 2025
Hilton San Diego Bayfront

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2501)
"Excellent and close to convention center."
The price is ¥23,774
¥33,838 total
includes taxes & fees
Jan 5 - Jan 6, 2025
Hard Rock Hotel San Diego

Comfort Inn Gaslamp Convention Center

2.5 star property
7.8 out of 10, Good, (1006)
"Overall it is a good place to stay within budget. "
The price is ¥15,811
¥17,818 total
includes taxes & fees
Dec 25 - Dec 26
Comfort Inn Gaslamp Convention Center

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
8.8 out of 10, Excellent, (1139)
"The attached restaurant has some issues, I asked if she could put on a Hockey Game and she "snapped back" at me that they only have local games. Well, the Padres are your only local team sister.... "
The price is ¥29,496
¥37,647 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Embassy Suites by Hilton San Diego Bay Downtown

Sheraton San Diego Resort

4.0 star property
8.0 out of 10, Very Good, (2497)
"I’d stay here again, beautiful property"
The price is ¥18,601
¥25,542 total
includes taxes & fees
Dec 29 - Dec 30
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.