Find Business Hotels in Downtown San Diego, CA

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 71 Downtown San Diego Business Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel
3.5 star property
8.2 out of 10, Very Good, (1376)
"Great stay great atmosphere"
The price is ¥19,799
¥25,732 total
includes taxes & fees
Nov 6 - Nov 7
The Sofia Hotel
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5568)
"I have no complaints aside from maybe switching to smart TV’s but that’s a minor nitpick. "
The price is ¥23,168
¥26,109 total
includes taxes & fees
Nov 23 - Nov 24
Wyndham San Diego Bayside
The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
8.8 out of 10, Excellent, (2133)
"Love this place!"
The price is ¥18,575
¥25,073 total
includes taxes & fees
Nov 25 - Nov 26
The Horton Grand, Downtown/Gaslamp Quarter
Manchester Grand Hyatt San Diego
4.0 star property
9.0 out of 10, Wonderful, (2927)
"We have very good experience. Specially your customer service Ria was very professional helpful We have excellent experience with her "
The price is ¥25,734
¥36,245 total
includes taxes & fees
Nov 26 - Nov 27
Manchester Grand Hyatt San Diego
Urban Boutique Hotel
3.0 star property
8.6 out of 10, Excellent, (1212)
"The front desk help could not be any bettr"
The price is ¥18,182
¥20,091 total
includes taxes & fees
Nov 24 - Nov 25
Urban Boutique Hotel
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1546)
"Great location. Easy access to Petco, Gaslamp district and Seaport Village. Great views and beautiful rooms."
The price is ¥23,992
¥34,277 total
includes taxes & fees
Dec 1 - Dec 2
Hilton San Diego Bayfront
Hard Rock Hotel San Diego
4.0 star property
8.8 out of 10, Excellent, (2518)
"Went here for the dodger game!! Beautiful and walkable places!!"
The price is ¥24,000
¥33,571 total
includes taxes & fees
Nov 24 - Nov 25
Hard Rock Hotel San Diego
Comfort Inn Gaslamp Convention Center
2.5 star property
7.8 out of 10, Good, (1012)
"The room I occupied was next to a parking lot and on some nights many homeless folks were making a racket late into the night and morning hours. Also, the window air conditioner was very musty smelling, so I just left it off."
The price is ¥15,714
¥17,709 total
includes taxes & fees
Dec 1 - Dec 2
Comfort Inn Gaslamp Convention Center
Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
8.8 out of 10, Excellent, (1138)
"Property/Location was wonderful, comes with a free breakfast. Extra charge for Daily Destination fee $25/day, like a resort fee but can be use for hotel credit. i just wished that parking ($65/day) would be included with the hotel fee."
The price is ¥29,783
¥37,877 total
includes taxes & fees
Dec 1 - Dec 2
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton San Diego Hotel and Marina
4.0 star property
8.0 out of 10, Very Good, (2480)
"Easy check in and out, magnificent views and very clean "
The price is ¥18,881
¥25,740 total
includes taxes & fees
Nov 24 - Nov 25
Sheraton San Diego Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Downtown San Diego

Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.