Find Business Hotels in Downtown San Diego, CA

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Pick from 71 Downtown San Diego Business Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel
Exterior
The Sofia Hotel
3.5 star property
8.2 out of 10, Very Good, (1375)
"Wonderful! Room was small but very clean and quiet. The only problem was an internet outage on the 2nd night. "
The price is ￥16,679
￥22,284 total
includes taxes & fees
Dec 19 - Dec 20
The Sofia Hotel
Wyndham San Diego Bayside
Exterior
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5523)
"Other than slow check in all was nice"
The price is ￥23,455
￥26,432 total
includes taxes & fees
Dec 3 - Dec 4
Wyndham San Diego Bayside
The Horton Grand, Downtown/Gaslamp Quarter
Courtyard
The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
8.8 out of 10, Excellent, (2141)
"It was great. Very convenient for meetings in the Convention Center."
The price is ￥21,089
￥27,937 total
includes taxes & fees
Nov 25 - Nov 26
The Horton Grand, Downtown/Gaslamp Quarter
Manchester Grand Hyatt San Diego
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego
4.0 star property
9.0 out of 10, Wonderful, (2865)
"Wonderful stay!"
The price is ￥24,835
￥35,323 total
includes taxes & fees
Dec 19 - Dec 20
Manchester Grand Hyatt San Diego
Urban Boutique Hotel
Check-in/check-out kiosk
Urban Boutique Hotel
3.0 star property
8.6 out of 10, Excellent, (1191)
"Good location … "
The price is ￥19,285
￥21,311 total
includes taxes & fees
Dec 17 - Dec 18
Urban Boutique Hotel
Hilton San Diego Bayfront
Outdoor pool, sun loungers
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1526)
"Room was still a little dirty after check in. Cleaning staff was friendly and re cleaned room for us. Overall a good stay. "
The price is ￥19,393
￥29,194 total
includes taxes & fees
Dec 23 - Dec 24
Hilton San Diego Bayfront
Hard Rock Hotel San Diego
Property amenity
Hard Rock Hotel San Diego
4.0 star property
8.8 out of 10, Excellent, (2510)
"I love how clean the hotel room was and the mini fridge was awesome."
The price is ￥27,198
￥37,298 total
includes taxes & fees
Dec 22 - Dec 23
Hard Rock Hotel San Diego
Comfort Inn Gaslamp Convention Center
Interior
Comfort Inn Gaslamp Convention Center
2.5 star property
7.8 out of 10, Good, (1007)
"It was good for a night stay. Breakfast very complete, and all employees were very kind"
The price is ￥14,785
￥16,663 total
includes taxes & fees
Dec 22 - Dec 23
Comfort Inn Gaslamp Convention Center
Embassy Suites by Hilton San Diego Bay Downtown
Exterior
Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
8.8 out of 10, Excellent, (1129)
"San Diego was fun and the hotel was great"
The price is ￥30,229
￥38,445 total
includes taxes & fees
Dec 20 - Dec 21
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton San Diego Hotel and Marina
3 outdoor pools, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Sheraton San Diego Hotel and Marina
4.0 star property
8.0 out of 10, Very Good, (2476)
"Clean, great view of bay, very helpful staff"
The price is ￥19,116
￥26,059 total
includes taxes & fees
Dec 16 - Dec 17
Sheraton San Diego Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.