Find Business Hotels in Downtown San Diego, CA

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Downtown San Diego Business Hotels

Tonight
Apr 21 - Apr 22
Tomorrow
Apr 22 - Apr 23
This weekend
Apr 25 - Apr 27
Next weekend
May 2 - May 4

Compare Downtown San Diego Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel
Exterior

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1464)
"very good, met our needs and staff was helpful and courteous."
The price is ￥16,571
￥22,540 total
includes taxes & fees
Apr 28 - Apr 29
The Sofia Hotel
Wyndham San Diego Bayside
Exterior

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (5691)
"Beautiful view"
The price is ￥22,963
￥26,624 total
includes taxes & fees
May 7 - May 8
Wyndham San Diego Bayside
The Horton Grand, Downtown/Gaslamp Quarter
Courtyard

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2317)
"The proximity to the convention center was great. I really appreciated that it was located on a quieter street, so it was not loud inside the room. Certainly a good consideration for my next trip when I’m around the Gaslamp District. "
The price is ￥18,813
￥25,048 total
includes taxes & fees
Apr 22 - Apr 23
The Horton Grand, Downtown/Gaslamp Quarter
Manchester Grand Hyatt San Diego
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2770)
"Beautiful property and helpful staff"
The price is ￥26,872
￥37,041 total
includes taxes & fees
Apr 22 - Apr 23
Manchester Grand Hyatt San Diego
Urban Boutique Hotel
Exterior

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1158)
"Great location. "
The price is ￥17,787
￥19,655 total
includes taxes & fees
Apr 22 - Apr 23
Urban Boutique Hotel
Hilton San Diego Bayfront
Outdoor pool, sun loungers

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very Good, (1505)
"Amazing stay for a weekend trip! Will definitely be coming back anytime I’m in San Diego!"
The price is ￥22,791
￥31,874 total
includes taxes & fees
May 10 - May 11
Hilton San Diego Bayfront
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2671)
"Perfect location for a weekend visit to the action in downtown San Diego. The hotel is very nice, the bar is fun and breakfast in the restaurant was delicious."
The price is ￥25,259
￥34,814 total
includes taxes & fees
Apr 22 - Apr 23
Hard Rock Hotel San Diego
Comfort Inn Gaslamp Convention Center
Lobby

Comfort Inn Gaslamp Convention Center

2.5 star property
7.8 out of 10, Good, (1013)
"Good customer service"
The price is ￥13,948
￥15,719 total
includes taxes & fees
Apr 22 - Apr 23
Comfort Inn Gaslamp Convention Center
Embassy Suites by Hilton San Diego Bay Downtown
Exterior

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1164)
"The room was nicely amenitized and modern. The staff was very friendly. The only parking is valet but they are very quick about brining your car and seem to have it down to a science. Very walkable area. "
The price is ￥25,258
￥32,473 total
includes taxes & fees
Apr 27 - Apr 28
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton San Diego Resort
View from room

Sheraton San Diego Resort

4.0 star property
8.2 out of 10, Very Good, (2618)
"The bartender and the bar inside the restaurant was awesome and very kind "
The price is ￥24,028
￥32,847 total
includes taxes & fees
Apr 27 - Apr 28
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Downtown San Diego

Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.