Find All Southern Illinois Hotels
We have found 992 Southern Illinois Hotels
- Giant City Lodge
- Riverview Mansion Hotel
- Mariner's Village Resort
- Total Solar Eclipse April 8 2024
- Carbondale Value Inn & Suites
- Econo Lodge
- Quality Inn Grayville, IL
- Sunset Motel
- Hyatt Regency St. Louis at The Arch
- Hollywood Casino & Hotel St. Louis
- Clayton Plaza Hotel & Extended Stay
- Drury Plaza Hotel St. Louis at the Arch
- Pear Tree Inn St. Louis Airport
- The Last Hotel
- Pear Tree Inn St. Louis Near Union Station
- 21C Museum Hotel St Louis
- Drury Inn & Suites St. Louis Union Station
- Casino Queen Hotel
- Moonrise Hotel
- Hilton St. Louis at the Ballpark
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.