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Compare 1,322 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Gamboa Rainforest Reserve

3.5 star property
7.8 out of 10, Good, (612)
"Beautiful hotel and wonderful location for hiking and birding. The swimming pool was immaculate. Food was overpriced, but really good. The resort is rather isolated, so you are paying for convenience. There is a local restaurant in town that is a half mile walk if you want to save."
The price is ¥20,995
¥23,095 total
includes taxes & fees
May 8 - May 9
Gamboa Rainforest Reserve

Summit Rainforest & Golf Resort

4.0 star property
8.4 out of 10, Very Good, (1001)
"The services were really good, such as the free shuttle services."
The price is ¥11,035
¥12,138 total
includes taxes & fees
Apr 27 - Apr 28
Summit Rainforest & Golf Resort

Holiday Inn Panama Canal by IHG

3.5 star property
8.4 out of 10, Very Good, (409)
"I chose this property as I wanted to be close to Miraflores Locks. I was not disappointed with my decision with the selection of the hotel. The property itself was very impressive, clean and well maintained. The hotel room as well as the Lobby area was very pleasing. Most importantly the staff - Fransisco, Bianca made me feel welcome and well attended to . Will surely stay here during my next visit"
The price is ¥13,599
¥17,321 total
includes taxes & fees
May 6 - May 7
Holiday Inn Panama Canal by IHG

Hotel y Casino Central Park Panama

3.0 star property
7.6 out of 10, Good, (393)
"Great location. Chinatown of Panama City (No Really). Close to famous Albrook Mall. Many food options within walkable distance. Wonderful staff. "
The price is ¥7,643
¥8,407 total
includes taxes & fees
May 8 - May 9
Hotel y Casino Central Park Panama

Best Western El Dorado Panama Hotel

3.0 star property
9.0 out of 10, Wonderful, (548)
"I would like to express my sincere gratitude to the exceptional Front Desk team—especially Alejandro, Jorge, and the administrative assistant whose name unfortunately escapes me at the moment. Throughout our stay, they demonstrated remarkable professionalism by being helpful in recommending various tourist sites and attractions, and consistently interactive, attentive, and highly efficient in addressing our needs. When we initially checked in and discovered that our assigned room next to the...
The price is ¥10,637
¥11,701 total
includes taxes & fees
May 14 - May 15
Best Western El Dorado Panama Hotel

SAND DIAMOND HOTEL

3.0 star property
8.6 out of 10, Excellent, (155)
"L'amabilité de la réception, la flex de la cuisine, "
The price is ¥18,014
¥19,815 total
includes taxes & fees
May 2 - May 3
SAND DIAMOND HOTEL

Radisson Colon 2,000 Hotel & Casino

4.0 star property
8.0 out of 10, Very Good, (753)
"Always a good choice for business, friendly staff and comfortable room! Breakfast is my favorite! "
The price is ¥15,584
¥68,611 total
includes taxes & fees
May 5 - May 6
Radisson Colon 2,000 Hotel & Casino

Albrook Inn

3.0 star property
7.8 out of 10, Good, (531)
"Great place near our airport to fly to Chitre Nice staff and nice little place to eat "
The price is ¥9,867
¥11,084 total
includes taxes & fees
Apr 25 - Apr 26
Albrook Inn

Hotel Sotelo

3.0 star property
7.6 out of 10, Good, (34)
"The hotel room was clean however the paint on the walls is dirty. The bedhead is discolored, bathroom mirror old and discolored. Air conditioner is very dirty. Bed is not comfortable. I ask front desk for ticker bedsheets buy there don't have. I booked for 6 days but leaves on the third day. The hotel is 5 minutes away from the free zone. Its the only thing i like."
The price is ¥5,719
¥6,291 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Sotelo

La Cubana Hotel & Residencial

2.5 star property
8.2 out of 10, Very Good, (75)
"The service "
The price is ¥4,246
¥4,671 total
includes taxes & fees
May 7 - May 8
La Cubana Hotel & Residencial

Hotel Andros

3.0 star property
7.8 out of 10, Good, (125)
"My stay is always great. The evening staff can do better with their attitudes "
The price is ¥5,790
¥6,369 total
includes taxes & fees
May 7 - May 8
Hotel Andros

Ramada Panama Centro Via Argentina

3.0 star property
7.4 out of 10, Good, (212)
"My stay was great "
The price is ¥8,506
¥9,357 total
includes taxes & fees
May 1 - May 2
Ramada Panama Centro Via Argentina

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (155)
"hermoso hotel familiar, con un jardín y un ambiente muy acogedores. desayuno básico. muy recomendado."
The price is ¥5,906
¥6,497 total
includes taxes & fees
May 9 - May 10
Panama House Bed & Breakfast

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1004)
"The service was great."
The price is ¥12,168
¥13,385 total
includes taxes & fees
Apr 27 - Apr 28
Novotel Panama City

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (843)
"The staff was very accommodating "
The price is ¥10,947
¥12,042 total
includes taxes & fees
May 22 - May 23
Best Western Plus Panama Zen Hotel

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Honestly i love ❤️ everything "
The price is ¥19,194
¥21,114 total
includes taxes & fees
May 3 - May 4
Marriott Panama Hotel

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1003)
"Wonderful "
The price is ¥11,681
¥12,849 total
includes taxes & fees
Apr 28 - Apr 29
TRYP by Wyndham Panamá Centro

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (339)
"Good value. Simple, comfortable and great staff!"
The price is ¥5,719
¥6,291 total
includes taxes & fees
Apr 27 - Apr 28
Hotel Milan

Waymore Hotel Spa & Casino

4.0 star property
9.0 out of 10, Wonderful, (234)
"The rooms were nice and we were very happy about the breakfast. The food was wonderful. I would recommend this hotel for anyone who is visiting Panama."
The price is ¥12,996
¥14,296 total
includes taxes & fees
May 18 - May 19
Waymore Hotel Spa & Casino

Hampton by Hilton Panama

3.0 star property
8.0 out of 10, Very Good, (1001)
"Love it definitely going back!!!"
The price is ¥11,545
¥12,699 total
includes taxes & fees
Apr 30 - May 1
Hampton by Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Rosa

Head to sights like Chagres River as you discover the local area in Santa Rosa.

Frequently asked questions

What's the best place for a stay in Santa Rosa?

Hotel Riu Plaza Panama, located 18.8 mi (30.2 km) from the heart of Santa Rosa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Riande Urban Hotel and JW Marriott Panama. See all available top hotels, or vacation rentals in Santa Rosa.

What are some of the best vacation home rentals that Santa Rosa has to offer?

Oasis with pool near panama canal: This vacation home rental near Santa Rosa offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa Rosa.

If I need to cancel my hotel reservation in Santa Rosa, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Rosa.

Where can I learn more about changing or cancelling my trip to Santa Rosa?

For more information about updating your trip to Santa Rosa or cancelling it, click here.

What is staying in Santa Rosa like?

Travelers to Santa Rosa will find plenty to explore and enjoy. A top sight in the area is Albrook Shopping Mall. There are 1322 hotels and other accommodations in the surrounding area. Find out more about Santa Rosa.

What are the top places to visit in Santa Rosa?

A favorite place to visit is Chagres River. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Rosa guide.

What's the seasonal weather like in Santa Rosa?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Santa Rosa are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.