Find hotels near Mayo Clinic, Rochester from ￥9,788

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
1
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare 432 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (608)
"Clean, friendly staff, and great location."
The price is ￥16,742
per night
Jul 4 - Jul 5
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Kahler Inn and Suites - Mayo Clinic Area
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, (1219)
"Liked how close it was to Mayo. The AC was very loud."
The price is ￥18,067
per night
Jun 8 - Jun 9
Kahler Inn and Suites - Mayo Clinic Area
Kahler Grand Hotel
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, (1015)
"Extremely close to Mayo Clinic Excellent staff"
The price is ￥23,187
per night
Jun 8 - Jun 9
Kahler Grand Hotel
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (564)
"Only problems: when I checked in the person in front of me was given 2 bottles of water. I did not receive any. When I asked, I was told I was not entitled to this because I booked through a third party! Also, the tv lost its signal several times."
The price is ￥16,651
per night
Jun 29 - Jun 30
Hyatt House Rochester/Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.8 out of 10, Good, (1006)
"Nice"
The price is ￥13,865
per night
Jun 30 - Jul 1
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (546)
"Super close to Mayo Clinic"
The price is ￥18,184
per night
Jul 1 - Jul 2
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1005)
"Pond next door, walking paths, shuttle to hospital and many things close by"
The price is ￥15,080
per night
Jun 30 - Jul 1
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
In-room safe, desk, iron/ironing board, free cribs/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very Good, (1007)
"The room was small, but okay for a single person. The bed was okay, it was clean. Loved the bench above the air conditioner/heater. The breakfast was standard cold and hot items, but not much for sitting, so you may need to eat in your room. The down fall was I could hear a TV going in the next room and in the other room, hear a phone alarm going off."
The price is ￥10,450
per night
Jun 9 - Jun 10
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Hampton Inn Rochester-South
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1011)
"Staff is awesome!! Room smelled wonderful but it is a weird layout. Only negative was the bed. Felt like the springs were eating me all night. "
The price is ￥14,246
per night
Jul 5 - Jul 6
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Blackout drapes, soundproofing, iron/ironing board, free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very Good, (396)
"The room was spacious and comfortable. The breakfast was excellent. It is an older building, so there were fewer electrical outlets but mostly this was not a serious problem."
The price is ￥13,757
per night
Jun 11 - Jun 12
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Residence Inn by Marriott Rochester Mayo Clinic Area South
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, (87)
"Our room was very clean and the layout was great!! Hotel was very clean and the price was amazing!! "
The price is ￥16,402
per night
Jul 1 - Jul 2
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (620)
"Great place to stay. Accessible to everything."
The price is ￥15,741
per night
Jul 5 - Jul 6
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, (284)
"Super nice and clean rooms with a lot of space"
The price is ￥18,363
per night
Jun 14 - Jun 15
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (615)
"Everything was very well done, all of the staff very friendlyand eager to please.. Breakfast was quite delicious. "
The price is ￥15,945
per night
Jul 5 - Jul 6
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Home2 Suites by Hilton Rochester Mayo Clinic Area
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (629)
"It’s close to the shopping center, Mayo Clinic and restaurants. The rooms are spacious. "
The price is ￥19,746
per night
Jul 7 - Jul 8
Home2 Suites by Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (339)
"Beautiful, clean property! "
The price is ￥26,323
per night
Jul 3 - Jul 4
Hilton Rochester Mayo Clinic Area
Quality Inn near Medical Center
Indoor spa tub
Quality Inn near Medical Center
2.5 star property
8.0 out of 10, Very Good, (503)
"Very quiet and close to Mayo. Nice pool and hottub. Full breakfast"
The price is ￥9,788
per night
Jul 3 - Jul 4
Quality Inn near Medical Center
Brentwood Inn & Suites
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, (1002)
"We spent several days at the Brentwood for medical appointments. The staff was very friendly, our room was very clean and we enjoyed our stay there very much. They provided a simple continental breakfast which was fine for our needs. When we needed to extend our stay, it was not a problem and we even got a lower rate. Prices were very reasonable."
The price is ￥18,519
per night
Jun 8 - Jun 9
Brentwood Inn & Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
8.2 out of 10, Very Good, (1011)
"Great location with the best staff & dining!!!!!!"
The price is ￥19,172
per night
Jun 9 - Jun 10
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Aspen Select
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Aspen Select
3.5 star property
8.6 out of 10, Excellent, (1004)
"I had family in the hospital and it was very close to Saint Francis hospital. "
The price is ￥19,451
per night
Jun 8 - Jun 9
Aspen Select
Don't see what you're looking for?
See all available properties in Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic hotels information

Number of reviews
14,388
Accommodation
432 hotels
Lowest Price
￥9,788
Highest Price
￥26,323

Hotels near Other Rochester Attractions

Image for Soldiers Field Veterans Memorial

Soldiers Field Veterans Memorial

4.5/5(30 reviews)

You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.

See properties
Soldiers Field Veterans Memorial

Frequently asked questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 168 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.

How many hotels will I be able to find near Mayo Clinic?

Expedia has 168 hotels and other accommodations within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?

For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Recent reviews of Mayo Clinic hotels
Expedia verified reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

5/5 Excellent
"Great location with the best staff & dining!!!!!!"
A verified traveler stayed at Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Posted 3 days ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area